Meet THCP & CBDP
A team of Italian scientists have recently announced the discovery of two new cannabinoids found in cannabis. Although exactly what the compounds do and how they affect the human body still largely remains a mystery, the researchers say their findings add to our understanding of the cannabis plant and highlights just how much remains to be discovered.
Tetrahydrocannabiphorol (THCP) has basically the same structure as tetrahydrocannabinol (THC) but is reportedly 30 times more potent than the well-known compound! In a pharmacological test, THCP “induced hypomotility, analgesia, catalepsy and decreased rectal temperature,” suggesting it has a THC-like effect on the body. However, it is not yet clear whether THCP is psychoactive or if it produces the same “stoned” effects as THC, although it appears to be even MORE active than THC at lower doses administered to mice.
The researchers also isolated and identified cannabidiphorol (CBDP), which is linked to CBD (an antioxidant, anti-inflammatory, anti-convulsant, and “antagonist of THC negative effects”).
To the best of their knowledge, the scientists write that a phytocannabinoid of such a structure (with a “linear alkyl side chain containing more than five carbon atoms”) has never been reported as naturally occurring. It could help the scientific world to understand why different strains produce different effects on the body, result in different feelings, and promote wellness and healing.
“A number of clinical trials and a growing body of literature provide real evidence of the pharmacological potential of cannabis and cannabinoids on a wide range of disorders from sleep to anxiety, multiple sclerosis, autism, and neuropathic pain,” write the authors in Scientific Reports, adding that they expect THCP to be endowed with "an even higher binding affinity for CB1 receptor [in the brain] and a greater cannabimimetic activity than THC itself.” Can’t wait to hear more about these two new heroes! ✌️💚🌱